Date: July 28, 2006 at 2:40:46 PM
Subject: TRANSFAC ® upgraded to version 10.2

We have made an upgrade to TRANSFAC ®, the transciption factor database. The new version includes new MATCH and PATCH versions (10.2) The number of entries in the database has grown considerably. Below are the current statistics:

Table	Description	Entries
FACTOR	Transcription factors, proteins that regulate gene transcription by sequence-specific interaction with DNA, and their interacting proteins.	8406
GENE	Genes with transcription factor binding sites (regulated genes) and/or genes encoding for transcription factors. (Also genes connected to one of our other databases.)	18495
SITE	DNA sequences to which binding of a transcription factor was shown.	17905
ChIP-chip	DNA fragments to which in vivo binding of a transcription factor was shown by ChIP-chip or related experiments.	12364
MATRIX	Nucleotide distribution matrices for the binding sites of a transcription factor.	811
CLASS	Transcription factor classes (leucine zipper, zinc finger, homeo domain ... factors).	57
CELL	Cellular source of the proteins that have been shown to interact with the sites.	2210
REFERENCE	Publications extracted for TRANSFAC entries (factor, site, etc.) with links to these entries and to PubMed.	13117

CGB Research account holders can access the TRANSFAC ® web interface.